— 藥理與非經腸給藥 · EASY · MCQ —
護理師照顧一位服用 Warfarin 的病人,應監測哪項檢驗指標以評估藥效?
A nurse is caring for a client receiving warfarin therapy. Which laboratory test should the nurse monitor to assess the therapeutic effect of this medication?
- AHemoglobin and hematocrit血紅素與血球容積
- BProthrombin time (PT) and INR✓ 正解凝血酶原時間(PT)與國際標準化比值(INR)
- CPlatelet count血小板計數
- DActivated partial thromboplastin time (aPTT)活化部分凝血活酶時間(aPTT)
— Explanation · 中文詳解 —
Warfarin 是一種維生素 K 拮抗劑,主要透過抑制肝臟凝血因子合成發揮作用。臨床上使用國際標準化比值(INR)作為調整藥物劑量的主要依據,PT 則是 INR 計算的基礎值。aPTT 主要用於監測肝素(Heparin)。
The International Normalized Ratio (INR) is the standard measure used to monitor the therapeutic effect of warfarin therapy. While prothrombin time (PT) is the basis for calculating INR, INR provides the standardized value for dose adjustment, unlike aPTT which monitors heparin.
✦ 台美臨床差異
台灣與美國臨床皆廣泛使用 INR 值作為調整 Warfarin 劑量的黃金標準。