— 藥理與非經腸給藥 · MEDIUM · MCQ —
病人獲開立萬古黴素（Vancomycin）。給予第二劑前，哪項行動優先？
A client is prescribed IV Vancomycin. Which action is the priority before administering the second dose?
- ADraw a trough level✓ 正解抽取谷濃度
- BCheck the patient's temperature測量病人體溫
- CVerify the blood glucose核對血糖
- DAssess for a rash評估是否有皮疹
— Explanation · 中文詳解 —
萬古黴素（Vancomycin）具有腎毒性與耳毒性，其治療窗（Therapeutic window）窄，必須透過血中濃度監測來調整給藥劑量。在給予第二劑前，護理師應配合檢驗室測量「谷值」（Trough level），這代表藥物在體內代謝至最低點時的濃度。若谷值過高，顯示藥物蓄積，需調整劑量以避免毒性反應。
Because vancomycin has a narrow therapeutic index and potential for nephrotoxicity and ototoxicity, obtaining a trough level ensures serum concentrations remain within the safe and effective range.