護理師準備給予病人萬古黴素（Vancomycin）。下列哪些護理措施是適當的？（選所有適合的）
A nurse is preparing to administer Vancomycin to a client. Which nursing interventions are appropriate? (Select all that apply.)
- AAdminister the infusion over at least 60 minutes✓ 正解輸注時間至少需 60 分鐘
- BMonitor the client for hypotension and flushing✓ 正解監測病人是否有低血壓與潮紅
- CDraw blood for trough levels 30 minutes before the next dose✓ 正解在下一次給藥前 30 分鐘抽取血液檢測谷濃度
- DDiscontinue the medication if the client develops localized redness at the site若病人於注射部位出現局部紅腫請停止用藥
- EAssess for signs of ototoxicity and nephrotoxicity✓ 正解評估耳毒性與腎毒性跡象
萬古黴素輸注速度過快易引發紅人症候群（Red Man Syndrome），故需維持至少一小時。藥物具腎毒性與耳毒性，治療過程中需定期監測血中谷濃度（Trough Level）並密切觀察腎功能指標與聽力變化。D 選項錯誤，局部紅腫應評估是否為血管炎或滲漏，而非逕自停藥。
Rapid infusion of vancomycin readily induces Red Man Syndrome, so the infusion should be administered over at least one hour. The drug is nephrotoxic and ototoxic; during therapy, the serum trough level must be checked periodically and renal function indicators and hearing changes must be closely monitored. Option D is incorrect, as local redness and swelling should be evaluated for phlebitis or extravasation rather than leading to unilateral discontinuation of the drug.
美國醫院藥局通常會自動提醒護理師檢測谷濃度；台灣常需護理師主動於醫囑系統排程提醒醫師開立檢驗單。