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藥理與非經腸給藥 · HARD · SATA

病人說出哪些話,表示需要對舌下含服硝酸甘油(Nitroglycerin)進行更多衛教?(選所有適合的)

Which statements by the client indicate a need for further teaching regarding sublingual nitroglycerin? (Select all that apply.)

  • AI should keep the tablets in the original amber glass bottle
    我應該將藥片保存在原廠的琥珀色玻璃瓶中
  • BI can take up to three tablets, five minutes apart
    我可以每隔五分鐘服用最多三片藥片
  • CI should swallow the tablet immediately with a full glass of water✓ 正解
    我應該立即用一杯水吞服藥片
  • DI might feel a tingling sensation under my tongue
    我可能會感到舌下有刺痛感
  • EI should store the medication in the bathroom cabinet for easy access✓ 正解
    我應該將藥物存放在浴室櫃中以方便取用
Explanation · 中文詳解

舌下含服硝酸甘油應含於舌下溶解,不能吞服,也不能喝水送服,否則藥效會經由胃腸道首渡效應而大幅降低。藥物應存放在避光、乾燥且陰涼處,浴室環境潮濕且溫差大,會加速藥物降解失效。刺痛感是藥物有效的表現,三片間隔五分鐘是正確的急救指導。

Sublingual nitroglycerin must be placed under the tongue to dissolve and absorb directly into the bloodstream, avoiding the gastrointestinal tract where first-pass metabolism would significantly reduce its efficacy. Additionally, the medication should be stored in a cool, dry place away from humidity, making bathroom storage inappropriate as moisture accelerates drug degradation.

✦ 台美臨床差異

兩地均強調藥物保存與含服方式,台灣居家環境潮濕,更需強調藥物存放的避光乾燥條件。

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