— 藥理與非經腸給藥 · MEDIUM · MCQ —
下列何項數據顯示 Warfarin 治療達到預期效果？
Which of the following findings would indicate a therapeutic response to warfarin therapy?
- AaPTT 60 seconds活化部分凝血活酶時間（aPTT）60秒
- BINR 2.5✓ 正解國際標準化比值（INR）2.5
- CPlatelet count 150,000/mm³血小板計數 150,000/mm³
- DPT 12 seconds凝血酶原時間（PT）12秒
— Explanation · 中文詳解 —
Warfarin 的監測指標為 INR（國際標準化比值），治療目標通常設定在 2.0 至 3.0 之間。PT（凝血酶原時間）雖然也是監測項目，但需換算成 INR 較準確。aPTT 是監測 Heparin 的指標，而血小板數值與抗凝血藥物療效判斷無關。
The monitoring indicator for warfarin is the INR (International Normalized Ratio), with a therapeutic goal typically set between 2.0 and 3.0. Although the PT (prothrombin time) is also monitored, conversion to INR provides greater accuracy. The aPTT is used for monitoring heparin, and the platelet count is unrelated to the assessment of anticoagulant efficacy.
✦ 台美臨床差異
美台皆以 INR 作為 Warfarin 的標準監測指標，臨床照護流程無顯著差異。