— 降低風險 · EASY · MCQ —
一位有心臟衰竭病史的病人預計接受顯影劑 CT 檢查。護理師預期在檢查後 48 小時內應暫停使用哪種藥物?
A client with a history of heart failure is scheduled for a CT scan with contrast. Which medication should the nurse expect to withhold for 48 hours after the procedure?
- AMetformin✓ 正解Metformin(二甲雙胍)
- BFurosemideFurosemide(呋塞米)
- CDigoxinDigoxin(地高辛)
- DLisinoprilLisinopril(賴諾普利)
— Explanation · 中文詳解 —
Metformin(雙胍類血糖藥)在顯影劑誘發急性腎損傷(CIN)時,可能導致藥物在體內積聚,進而引發嚴重的乳酸中毒(Lactic Acidosis)。因此,臨床指引建議在接受含碘顯影劑檢查後的 48 小時內暫停使用 Metformin,待確認腎功能正常後再恢復。
When contrast-induced acute kidney injury (CIN) occurs, metformin (a biguanide antidiabetic) may accumulate in the body and precipitate severe lactic acidosis. For this reason, clinical guidelines recommend withholding metformin for 48 hours after iodinated contrast studies, restarting it only after renal function is confirmed to be normal.
✦ 台美臨床差異
美國放射學會(ACR)指引非常強調 Metformin 的管理;台灣各醫院放射科也有類似的標準核對清單。