護理師正在查看一位因深部靜脈栓塞接受肝素（heparin）治療病人的檢驗結果。aPTT 為 120 秒（對照值為 35 秒）。護理師首要採取的措施為何？
A nurse is reviewing the laboratory results of a client receiving heparin for a deep vein thrombosis. The activated partial thromboplastin time (aPTT) is 120 seconds (Control: 35 seconds). Which action is the priority?
- AIncrease the heparin infusion rate增加肝素輸注速率
- BStop the heparin infusion and notify the healthcare provider✓ 正解停止肝素輸注並通知醫療提供者
- CContinue the infusion at the current rate以目前速率繼續輸注
- DAdminister Vitamin K as an antidote給予維生素 K 作為解毒劑
aPTT 的治療範圍通常為對照值的 1.5 到 2.5 倍（約 52.5-87.5 秒）。120 秒已遠超治療範圍，增加出血風險。肝素半衰期短，首要動作是停藥並通知醫師。維生素 K 是 Warfarin 的拮抗劑，Protamine sulfate 才是肝素的拮抗劑。
An aPTT of 120 seconds is significantly above the therapeutic range, indicating a high risk for bleeding complications due to excessive anticoagulation. The priority action is to stop the heparin infusion immediately to prevent hemorrhage and notify the healthcare provider for further orders, such as administering protamine sulfate if necessary.
在美國，醫院通常有肝素調劑協定（Heparin Protocol），護理師可依 aPTT 自行調整劑量；台灣多需醫師確認後調整。