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藥理與非經腸給藥 · EASY · MCQ

護理師準備給予病人華法林(Warfarin)。給藥前應審核哪項實驗室數值?

A nurse is administering a dose of warfarin to a client. Which laboratory value should the nurse review prior to administration?

  • AActivated partial thromboplastin time (aPTT)
    活化部分凝血活酶時間 (aPTT)
  • BProthrombin time (PT) and INR✓ 正解
    凝血酶原時間 (PT) 和國際標準比值 (INR)
  • CHemoglobin and hematocrit
    血紅素和血球容積
  • DPlatelet count
    血小板計數
Explanation · 中文詳解

華法林(Warfarin)是一種口服抗凝血劑,透過抑制維生素 K 依賴性凝血因子(II, VII, IX, X)來發揮作用。為了監測其抗凝血效果並調整劑量,臨床上使用凝血酶原時間(PT)及其標準化比值(INR)。INR 是目前國際公認的標準,給藥前必須確認數值在治療目標範圍內,以避免發生出血風險或抗凝血效果不足。

Warfarin inhibits vitamin K-dependent clotting factors, so the prothrombin time (PT) and International Normalized Ratio (INR) must be reviewed prior to administration. These values determine if the client is within the therapeutic range to ensure efficacy while minimizing bleeding risks.

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