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藥理與非經腸給藥 · EASY · MCQ

下列哪種藥物在給藥前,護理師必須測量完整一分鐘的心尖脈?

Which of the following medications requires the nurse to check the apical pulse for one full minute before administration?

  • AAmlodipine
    Amlodipine(氨氯地平)
  • BFurosemide
    Furosemide(呋塞米)
  • CDigoxin✓ 正解
    Digoxin(地高辛)
  • DLisinopril
    Lisinopril(賴諾普利)
Explanation · 中文詳解

地高辛(Digoxin)具有正性肌力與負性頻率作用,能增強心肌收縮力並減慢房室傳導。由於該藥物具有狹窄的治療窗且易產生毒性,尤其是心跳過慢(Bradycardia)或心律不整,因此在給藥前測量心尖脈(Apical pulse)極為重要。臨床標準通常規定,若成人心跳低於每分鐘 60 次,應暫停給藥並通知醫師,以防止嚴重的心動過緩。

Digoxin has positive inotropic and negative chronotropic effects, increasing myocardial contractility and slowing AV conduction. Because the drug has a narrow therapeutic window and is prone to toxicity, particularly bradycardia and arrhythmias, measurement of the apical pulse before administration is essential. Clinical standard practice dictates that if an adult's heart rate is below 60 beats per minute, the dose should be held and the physician notified, in order to prevent severe bradycardia.

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