護理師準備給予第一型糖尿病病人甘精胰島素（Glargine）。關於此藥物，下列敘述何者正確？
A nurse is preparing to administer insulin glargine to a patient with Type 1 diabetes. Which statement is correct regarding this medication?
- AIt should be mixed with NPH insulin應與 NPH 胰島素混合
- BIt must be administered before meals必須在餐前給藥
- CIt has a peak effect in 2 to 4 hours在 2 至 4 小時內達藥效高峰
- DIt provides a basal level of insulin throughout the day✓ 正解提供全天基礎劑量的胰島素
甘精胰島素（Glargine）是一種長效型（Long-acting）胰島素，其藥物動力學設計為無尖峰（Peakless），能提供 24 小時穩定的基礎胰島素水平。這與人體胰臟在空腹時持續分泌的基礎胰島素相似。由於其 pH 值偏酸，不可與其他胰島素混合，以免影響藥效。此類胰島素通常每日固定時間給藥，作為控制血糖的基礎背景，而非針對餐後血糖波動的速效胰島素。
Insulin glargine is a long-acting insulin whose pharmacokinetic profile is designed to be peakless, providing a steady basal insulin level over 24 hours. This is similar to the basal insulin secreted continuously by the pancreas during fasting. Because its pH is acidic, it cannot be mixed with other insulins or its activity will be compromised. This type of insulin is usually administered at the same time each day to provide a stable background of glycemic control, rather than as a rapid-acting insulin targeted at postprandial glucose fluctuations.