— 藥理與非經腸給藥 · EASY · MCQ —
在給予病人乙型阻斷劑（Beta-blocker）前，下列哪項評估最為關鍵？
Which of the following assessments is most critical before administering a beta-blocker to a client?
- ACheck for peripheral edema檢查周邊水腫
- BVerify the blood pressure and pulse rate✓ 正解確認血壓和脈搏率
- CAssess the client's skin turgor評估病人的皮膚彈性
- DAsk about recent dietary intake詢問最近的飲食攝取
— Explanation · 中文詳解 —
乙型阻斷劑（Beta-blocker）的主要藥理機轉是競爭性阻斷心臟的 Beta-1 受體，從而減慢心率並降低心肌收縮力。若病人現有心跳過慢（Bradycardia）或低血壓（Hypotension），給藥將進一步抑制心血管功能，可能導致休克或心臟停跳。因此，給藥前必須確認生命徵象，這是藥物安全給藥的關鍵環節。
The primary pharmacological mechanism of beta-blockers is competitive blockade of the cardiac beta-1 receptors, which slows the heart rate and decreases myocardial contractility. If the client already has bradycardia or hypotension, administering the medication will further suppress cardiovascular function and may lead to shock or cardiac arrest. Therefore, vital signs must be verified before administration; this is a critical step in safe medication administration.