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藥理與非經腸給藥 · MEDIUM · MCQ

哪類藥物通常被禁止用於氣喘病人?

Which medication category is typically contraindicated for a client with asthma?

  • AStatins
    他汀類藥物
  • BBeta-blockers✓ 正解
    乙型交感神經阻斷劑
  • CCalcium channel blockers
    鈣離子通道阻斷劑
  • DACE inhibitors
    血管張力素轉化酶抑制劑
Explanation · 中文詳解

氣喘(Asthma)病人應避免使用會導致支氣管收縮的藥物。乙型阻斷劑(Beta-blockers)主要分為非選擇性與選擇性。非選擇性 Beta-blockers(如 Propranolol)會同時阻斷 Beta-1(心臟)與 Beta-2(支氣管平滑肌)受體,導致支氣管痙攣,誘發急性氣喘發作。即使是選擇性 Beta-1 阻斷劑,在高劑量下也可能失去選擇性而影響肺部,因此氣喘病人使用時需極度謹慎或禁用。

Clients with asthma should avoid medications that cause bronchoconstriction. Beta-blockers are divided into non-selective and selective agents. Non-selective beta-blockers (such as propranolol) block both beta-1 (cardiac) and beta-2 (bronchial smooth muscle) receptors, leading to bronchospasm and triggering an acute asthma attack. Even selective beta-1 blockers can lose their selectivity at high doses and affect the lungs, so they must be used with extreme caution or avoided altogether in clients with asthma.

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