— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師正給予預定的甘精胰島素 (insulin glargine) 劑量。這種類型的胰島素有何關鍵特徵？
A nurse is administering a scheduled dose of insulin glargine. What is a key characteristic of this type of insulin?
- AIt has a short duration of action.作用時間短暫
- BIt has no peak effect.✓ 正解無作用高峰
- CIt has a rapid onset of action.起效迅速
- DIt is taken only before meals.僅在餐前服用
— Explanation · 中文詳解 —
甘精胰島素（insulin glargine）屬於長效型（long-acting）胰島素。其分子結構設計使其在生理 pH 值下溶解度低，在注射部位形成微沉澱，從而緩慢、穩定地釋放入血循環。這種特性使其提供平穩的基礎胰島素（basal insulin）覆蓋，不會產生明顯的藥效高峰（peakless），從而降低低血糖發生的風險。
Insulin glargine is a long-acting insulin. Its molecular design has low solubility at physiologic pH, forming a microprecipitate at the injection site that slowly and steadily releases into the bloodstream. This provides smooth basal insulin coverage with no pronounced peak (peakless), reducing hypoglycemia risk.