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藥理與非經腸給藥 · MEDIUM · MCQ

病人出院帶回左旋甲狀腺素(Levothyroxine),哪項衛教最重要?

Which instruction is most important for a client being discharged with levothyroxine?

  • AMonitor blood pressure daily
    每天監測血壓
  • BTake the medication on an empty stomach in the morning✓ 正解
    早上空腹服用藥物
  • CTake it with an antacid to prevent indigestion
    與制酸劑一起服用以預防消化不良
  • DStop the medication if heart palpitations occur
    若出現心悸則停止用藥
Explanation · 中文詳解

左旋甲狀腺素(Levothyroxine)的吸收極易受到胃腸道內容物與藥物的干擾,尤其是鈣、鎂、鐵製劑或制酸劑。為了確保藥物能被穩定吸收並維持穩定的血中甲狀腺素濃度,臨床標準建議必須在早晨空腹服用,且應與早餐間隔 30-60 分鐘。若病人不遵守此規定,可能導致劑量不足或濃度波動,進而影響甲狀腺功能的控制。

The absorption of levothyroxine is highly susceptible to interference from gastrointestinal contents and other medications, particularly calcium, magnesium, iron preparations, and antacids. To ensure stable absorption and maintain steady serum thyroid hormone levels, clinical standards recommend that the drug be taken on an empty stomach in the morning, 30-60 minutes before breakfast. If the client does not adhere to this guidance, the dose may be insufficient or serum levels may fluctuate, thereby affecting control of thyroid function.

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