— 藥理與非經腸給藥 · MEDIUM · MCQ —
一位病人被處方使用單硝酸異山梨酯 (isosorbide mononitrate) 治療心絞痛。護理師應指示病人如何服用此藥物？
A client is prescribed isosorbide mononitrate for angina. The nurse should instruct the client to take this medication:
- ATwice a day, 6 hours apart.✓ 正解每日兩次，間隔 6 小時
- BAt bedtime only.僅於就寢時
- COnce daily in the morning.每日早晨一次
- DAs needed for chest pain.胸痛時按需服用
— Explanation · 中文詳解 —
單硝酸異山梨酯 (isosorbide mononitrate) 是長效型硝酸鹽類藥物，主要用於預防心絞痛。為了避免耐受性 (tolerance) 的產生，身體需要有「無藥期間」(nitrate-free interval)，因此通常採取每日兩次、間隔約 6-8 小時的給藥方式，以確保藥效穩定且不會讓心臟產生抗藥性。
Isosorbide mononitrate is a long-acting nitrate primarily used for the prevention of angina. To avoid the development of tolerance, the body needs a nitrate-free interval; therefore, the drug is usually given twice daily, approximately 6-8 hours apart, to maintain stable therapeutic effects without inducing tolerance.