護理師準備對一位有深部靜脈栓塞病史的病人給予 warfarin。給藥前應檢查哪項實驗室數據?
A nurse is preparing to administer warfarin to a client with a history of deep vein thrombosis. Which laboratory value should the nurse review before administration?
- AInternational Normalized Ratio (INR)✓ 正解國際標準化比值(INR)
- BPartial thromboplastin time (PTT)部分凝血活酶時間(PTT)
- CHemoglobin level血紅素濃度
- DPlatelet count血小板計數
Warfarin(Coumadin)是一種維生素 K 拮抗劑,其抗凝血效果需透過監測 INR 來進行調整,以確保治療範圍(通常在 2-3 之間)。PTT 主要用於監測肝素(Heparin)的療效。雖然血小板與血紅素對病人整體狀況重要,但對於 warfarin 的劑量調整無直接參考價值。
Warfarin (Coumadin) is a vitamin K antagonist, and its anticoagulant effect must be monitored and titrated using the INR to ensure the value remains within the therapeutic range (commonly 2-3). PTT is primarily used to monitor heparin therapy. While platelet count and hemoglobin level are important indicators of the client's overall status, they have no direct value in adjusting the warfarin dose.
台美皆以 INR 為監測標準;美國常設有抗凝血劑衛教護理師(Anticoagulation Nurse),台灣則多由醫師依數據調整處方。