— 藥理與非經腸給藥 · MEDIUM · MCQ —
一位心房顫動病人長期服用 Warfarin，下列何項檢查結果顯示已達到治療目標？
A client is prescribed Warfarin for atrial fibrillation. Which findings indicate the therapeutic goal has been achieved?
- APTT 60 secondsPTT 60 秒
- BINR 2.5✓ 正解INR 2.5
- CPT 12 secondsPT 12 秒
- DPlatelet count 150,000/mm3血小板計數 150,000/mm3
— Explanation · 中文詳解 —
服用 Warfarin 的治療目標通常是將 INR 維持在 2.0 至 3.0 之間（針對心房顫動）。PT 正常值約 11-13 秒，PTT 是監測 Heparin 的指標，血小板數量則與抗凝血藥效監測無直接關聯。
For clients taking warfarin, the therapeutic goal is indicated by an International Normalized Ratio (INR) between 2.0 and 3.0. Unlike heparin, which is monitored via PTT, warfarin efficacy is assessed through INR, making a value of 2.5 the correct indicator of therapeutic anticoagulation.
✦ 台美臨床差異
美國抗凝血劑藥師管理（Anticoagulation Clinic）極普遍，台灣多由醫師決定劑量，護理師輔助檢驗數值監測。