— 藥理與非經腸給藥 · EASY · MCQ —
病人靜脈注射萬古黴素時，護理師觀察到頸部與臉部潮紅。此時應採取何項行動？
A client is prescribed intravenous vancomycin. The nurse notes the client develops flushing of the face and neck shortly after the infusion begins. Which action should the nurse take?
- AIncrease the rate of infusion增加輸注速率
- BStop the infusion immediately✓ 正解立即停止輸注
- CContinue the infusion as this is expected繼續輸注，因為這是預期中的反應
- DAdminister an antihistamine給予抗組織胺藥物
— Explanation · 中文詳解 —
此反應為紅人症候群（Red Man Syndrome），係因萬古黴素輸注速度過快導致組織胺大量釋放。首要處置為立即停止輸注，待症狀緩解後，再依醫囑以較慢速度重新開始輸注。此為輸注反應，非過敏性休克，但仍需暫停以避免惡化。
This reaction is Red Man Syndrome, caused by infusion of vancomycin at too rapid a rate, resulting in massive histamine release. The priority intervention is to stop the infusion immediately; after symptoms subside, the infusion may be restarted at a slower rate per provider orders. This is an infusion reaction rather than anaphylaxis, but pausing is still required to prevent worsening.
✦ 台美臨床差異
台美對此反應的處理原則一致，皆強調減慢輸注速度或延長輸注時間至 60-90 分鐘以上。