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藥理與非經腸給藥 · EASY · MCQ

護理師準備對心臟衰竭病人給予地高辛(Digoxin),若發現下列何種情況應暫停給藥?

A nurse is administering a dose of digoxin to a patient with heart failure. Which assessment finding should lead the nurse to withhold the medication?

  • ASerum potassium level of 4.2 mEq/L
    血清鉀濃度為4.2 mEq/L
  • BBlood pressure of 110/70 mmHg
    血壓為110/70 mmHg
  • CApical heart rate of 52 beats per minute✓ 正解
    心尖脈搏為每分鐘52次
  • DPresence of 1+ pitting edema in lower extremities
    下肢存在1+凹陷性水腫
Explanation · 中文詳解

地高辛(Digoxin)具有正性肌力作用(增加心肌收縮力)與負性變時作用(減慢心跳)。成人給藥的臨床安全標準通常為心跳(Apical heart rate)大於 60 次/分。若心跳小於 60 次/分,給藥可能引發嚴重緩脈(Bradycardia)或心律不整,因此護理師必須暫停給藥並通知醫師,以防藥物中毒。

Digoxin has a positive inotropic effect (increasing myocardial contractility) and a negative chronotropic effect (slowing the heart rate). The clinical safety standard for administration in adults is generally an apical heart rate greater than 60 beats/min. If the heart rate is less than 60 beats/min, administration may precipitate severe bradycardia or arrhythmias; therefore, the nurse must withhold the medication and notify the provider to prevent drug toxicity.

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