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藥理與非經腸給藥 · HARD · SATA

下列哪些藥物在對磺胺類(sulfa)過敏的病人中是禁忌的?(選所有適合的)

Which of the following medications are contraindicated in clients with a sulfa allergy? (Select all that apply.)

  • ATrimethoprim-Sulfamethoxazole✓ 正解
    Trimethoprim-Sulfamethoxazole(複方磺胺甲惡唑)
  • BHydrochlorothiazide✓ 正解
    Hydrochlorothiazide(氫氯噻嗪)
  • CCelecoxib✓ 正解
    Celecoxib(塞來昔布)
  • DFurosemide✓ 正解
    Furosemide(呋塞米)
  • EAcetaminophen
    Acetaminophen(乙醯胺酚)
Explanation · 中文詳解

磺胺過敏的交叉反應常發生在同樣具有磺胺基團的藥物上,包括 Trimethoprim-Sulfamethoxazole(抗生素)、Thiazide 利尿劑(如 HCTZ)、Loop 利尿劑(如 Furosemide)以及部分 COX-2 抑制劑(如 Celecoxib)。Acetaminophen 結構完全不同,無此顧慮。

Cross-reactivity in sulfa allergy commonly occurs with other medications that also contain a sulfonamide moiety, including trimethoprim-sulfamethoxazole (an antibiotic), thiazide diuretics (such as hydrochlorothiazide), loop diuretics (such as furosemide), and some COX-2 inhibitors (such as celecoxib). Acetaminophen has a completely different structure and poses no such concern.

✦ 台美臨床差異

美國醫院藥局系統常會自動標示過敏警示,台灣護理師則需仰賴藥物過敏紀錄卡。

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