— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師審核病人的用藥清單。哪對藥物交互作用需要護理介入？
A nurse is reviewing a client's medication list for interactions. Which pair of medications indicates a need for nursing intervention?
- AMetformin and InsulinMetformin 和 Insulin
- BAspirin and AcetaminophenAspirin 和 Acetaminophen
- CLisinopril and Potassium supplements✓ 正解Lisinopril 和 Potassium supplements
- DFurosemide and Potassium supplementsFurosemide 和 Potassium supplements
— Explanation · 中文詳解 —
Lisinopril 是血管張力素轉化酶抑制劑（ACE Inhibitor），其作用機轉會導致腎臟減少鉀離子排泄。若病人同時服用鉀補充劑（Potassium supplements），極易導致血鉀過高（Hyperkalemia），嚴重時可能引發致命的心律不整。這是臨床上重要的藥物交互作用，護理師在審核用藥清單時必須特別留意並介入。
Lisinopril, an ACE inhibitor, reduces aldosterone secretion, which decreases potassium excretion and increases the risk of hyperkalemia. Combining lisinopril with potassium supplements significantly elevates this risk, potentially leading to life-threatening cardiac arrhythmias. Nursing intervention is required to review and adjust the medication regimen to prevent dangerous electrolyte imbalances.