— 藥理與非經腸給藥 · EASY · MCQ —
慢性腎臟病病人正接受紅血球生成素（Epoetin alfa）。哪項實驗室結果顯示治療有效？
A client with chronic kidney disease is receiving epoetin alfa. Which laboratory result indicates the medication is effective?
- ADecrease in serum potassium血清鉀降低
- BIncrease in hematocrit and hemoglobin✓ 正解血球容積比和血色素增加
- CDecrease in blood urea nitrogen尿素氮降低
- DIncrease in serum iron levels血清鐵水平增加
— Explanation · 中文詳解 —
Epoetin alfa 的作用是刺激骨髓產生紅血球。因此，治療有效的指標是血紅素（Hb）和血球容積比（Hct）上升。這通常用於治療慢性腎病引起的貧血。需注意血紅素上升過快或過高（>11 g/dL）會增加血栓與高血壓風險。
Epoetin alfa stimulates red blood cell production, so effectiveness is indicated by an increase in hematocrit and hemoglobin levels. This medication is used to treat anemia associated with chronic kidney disease. It does not directly lower BUN or potassium, and serum iron may decrease as it is utilized for erythropoiesis.
✦ 台美臨床差異
美國 FDA 對 Epoetin 有黑盒警告，強調血紅素超過 11 g/dL 時需減量或停藥；台灣健保給付亦有類似的血紅素監控標準。