— 藥理與非經腸給藥 · HARD · MCQ —
對於因類風濕性關節炎服用 Methotrexate 的病人,哪項衛教至關重要?
Which instruction is critical for a patient receiving Methotrexate for rheumatoid arthritis?
- AIncrease intake of caffeine增加咖啡因攝取
- BAvoid pregnancy while on the medication✓ 正解服藥期間避免懷孕
- CStop taking immediately if you get a cold感冒時立即停藥
- DTake with meals to prevent diarrhea隨餐服用以預防腹瀉
— Explanation · 中文詳解 —
Methotrexate 屬於葉酸拮抗劑(Folate antagonist),臨床上用於治療類風濕性關節炎及多種癌症。此藥具有高度致畸胎性(Teratogenicity),可干擾細胞分裂並導致胎兒畸形或死亡。護理師進行衛教時,必須強調在用藥期間及停藥後的建議時間內採取有效的避孕措施。臨床思路應優先考慮藥物的安全性與禁忌症。
Methotrexate is a folate antagonist with high teratogenic potential, capable of causing fetal malformations or death by interfering with cell division. Therefore, the most critical instruction is to avoid pregnancy during therapy and for a specified period afterward. Patients must be educated on using effective contraception to prevent these severe adverse outcomes.
✦ 台美臨床差異
在美國臨床,護理師需確認病人是否有使用避孕藥物或計畫,並記錄在衛教紀錄中,以符合法律防禦性護理。