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藥理與非經腸給藥 · MEDIUM · MCQ

病人因深層靜脈栓塞接受肝素(Heparin)靜脈輸注,護理師應監測哪項檢驗值以調整輸注速度?

A client is prescribed intravenous heparin therapy for deep vein thrombosis. Which laboratory value should the nurse monitor to adjust the heparin infusion rate?

  • APlatelet count
    血小板計數
  • BInternational Normalized Ratio (INR)
    國際正常化比值(INR)
  • CProthrombin time (PT)
    凝血酶原時間(PT)
  • DActivated partial thromboplastin time (aPTT)✓ 正解
    活化部分凝血活酶時間(aPTT)
Explanation · 中文詳解

肝素(Heparin)會延長內因性凝血路徑,臨床上使用 aPTT 來監測其抗凝血療效,以決定是否需根據醫院的 Nomogram 調整輸注劑量。PT/INR 主要用於監測口服抗凝血劑 Warfarin 的效果。

Activated partial thromboplastin time (aPTT) is the primary laboratory test used to monitor the therapeutic effect of intravenous heparin, as it reflects the intrinsic coagulation pathway. The results guide dosage adjustments according to institutional nomograms to prevent clotting or bleeding complications.

✦ 台美臨床差異

兩地均採用 aPTT 監測,但在台灣臨床經常需同時參考抗凝血因子活性(Anti-Xa)以獲得更精準數據。

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