對於完全沒有接種過百日咳疫苗（Tdap）紀錄的成人，下列哪種接種排程是正確的？
Which of the following immunization schedules is correct for an adult who has no record of prior Tdap (Tetanus, Diphtheria, Pertussis) vaccination?
- AThree doses of Tdap administered one month apart間隔一個月施打三劑 Tdap
- BA series of three Tdap injections, then one booster annually施打三劑 Tdap 系列疫苗，之後每年加強一劑
- COne dose of Tdap, followed by Td boosters every 10 years✓ 正解施打一劑 Tdap，之後每 10 年施打一次 Td 加強劑
- DOnly one dose of Tdap is required, and no further boosters are needed只需施打一劑 Tdap，且不需要進一步的加強劑
根據美國預防接種諮詢委員會（ACIP）的指引，針對未曾接種過百日咳疫苗（Tdap）的成人，必須優先補足 Tdap 劑量以提供對百日咳（Pertussis）的免疫力。一旦接種過一劑 Tdap，後續的補強接種（Booster）則回歸到每 10 年一次的 Td（破傷風與白喉）即可。此排程旨在確保成人對這三種疾病具備長期保護力，特別是針對百日咳的群體免疫。
Adults with no prior Tdap history should receive one dose of Tdap to protect against pertussis, followed by Td boosters every 10 years thereafter. This schedule ensures long-term immunity against tetanus, diphtheria, and pertussis without requiring annual or multiple initial doses. Adhering to ACIP guidelines helps maintain herd immunity and individual protection.
台灣與美國指引在成人疫苗接種上大方向一致，但美國特別強調孕婦在每次懷孕期間（通常在 27-36 週）皆需接種一劑 Tdap，以保護新生兒，此為台灣臨床較少強調的常規。