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藥理與非經腸給藥 · MEDIUM · SATA

病人正接受靜脈肝素(Heparin)治療。護理師應監測哪些檢驗數值以評估療效?(選所有適合的)

A client is prescribed intravenous heparin therapy. Which laboratory values should the nurse monitor to assess the therapeutic effect of the drug? (Select all that apply.)

  • AActivated partial thromboplastin time (aPTT)✓ 正解
    活化部分凝血活酶時間 (aPTT)
  • BProthrombin time (PT)
    凝血酶原時間 (PT)
  • CInternational normalized ratio (INR)
    國際標準化比值 (INR)
  • DAnti-Xa assay✓ 正解
    抗因子Xa檢測 (Anti-Xa assay)
  • EPlatelet count✓ 正解
    血小板計數
Explanation · 中文詳解

肝素主要透過監測 aPTT 或 Anti-Xa 來評估凝血狀態。PT 和 INR 是用來監測華法林(Warfarin)的。此外,監測血小板計數(Platelet count)是為了預防肝素引起的血小板減少症(HIT),這是臨床重要的安全監測項目。

The therapeutic effect of intravenous heparin is monitored using activated partial thromboplastin time (aPTT) or anti-Xa assays. Additionally, platelet counts must be regularly checked to detect Heparin-Induced Thrombocytopenia (HIT), a serious adverse reaction, whereas PT and INR are used for warfarin monitoring.

✦ 台美臨床差異

台灣臨床多以 aPTT 為主,部分醫學中心已逐漸導入 Anti-Xa 監測。

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