病人因深層靜脈栓塞正接受連續肝素滴注。護理師應監測何項檢驗值以評估治療效果？
A client is receiving a continuous heparin infusion for deep vein thrombosis. Which laboratory value should the nurse monitor to determine the therapeutic effect?
- APlatelet count血小板計數
- BInternational normalized ratio (INR)國際標準化比值 (INR)
- CProthrombin time (PT)凝血酶原時間 (PT)
- DActivated partial thromboplastin time (aPTT)✓ 正解活化部分凝血活酶時間 (aPTT)
肝素（Heparin）主要透過拮抗凝血因子達到抗凝血作用，臨床標準監測指標為 aPTT，治療目標通常為對照組的 1.5 到 2.5 倍。PT/INR 主要用於監測口服抗凝劑 Warfarin。血小板計數雖需監測以防肝素引起的血小板低下症（HIT），但非用於評估抗凝效果。
Activated partial thromboplastin time (aPTT) is the standard laboratory test used to monitor the therapeutic effectiveness of intravenous heparin, with a target range typically 1.5 to 2.5 times the control value. While platelet counts are monitored to detect heparin-induced thrombocytopenia, they do not assess anticoagulation efficacy. Prothrombin time (PT) and international normalized ratio (INR) are used to monitor oral anticoagulants like warfarin.
台美臨床對於肝素輸注皆遵循嚴格的抗凝血劑流程（Nomogram），護理師需依據當前 aPTT 值調整輸注速度。