— 降低風險 · HARD · SATA —
護理師正在評估一位患有庫欣氏症（Cushing's disease）的病人。預期會觀察到哪些發現？（選所有適合的）
A nurse is assessing a client with Cushing's disease. Which findings should the nurse expect to observe? (Select all that apply.)
- AMoon face✓ 正解月圓臉
- BWeight loss體重減輕
- CPurple striae on the abdomen✓ 正解腹部出現紫色紋路
- DThinning of the skin✓ 正解皮膚變薄
- EHyperglycemia✓ 正解高血糖
— Explanation · 中文詳解 —
庫欣氏症（Cushing's disease）起因於皮質醇（Cortisol）分泌過多。皮質醇是一種糖皮質素，具有促進蛋白質分解、抑制免疫、升高血糖及改變脂肪分佈的作用。臨床表現為典型的「向心性肥胖」，即脂肪堆積在軀幹與臉部，導致月亮臉與水牛肩；同時因蛋白質分解導致皮膚變薄、出現紫色妊娠紋，並因肝醣新生作用導致高血糖。
Cushing's disease results from excess cortisol, causing fat redistribution to the face and trunk (moon face), protein catabolism leading to thin skin and purple striae, and increased gluconeogenesis resulting in hyperglycemia.