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藥理與非經腸給藥 · EASY · MCQ

護理師準備給予心衰竭病人地高辛(Digoxin),若出現下列何項數據,必須暫停給藥?

A nurse is administering a dose of digoxin to a patient with heart failure. Before giving the medication, which finding necessitates withholding the dose?

  • AApical pulse rate of 52 beats per minute✓ 正解
    心尖脈搏速率為每分鐘 52 下
  • BRespiratory rate of 16 breaths per minute
    呼吸頻率為每分鐘 16 次
  • CPotassium level of 4.2 mEq/L
    鉀離子濃度為 4.2 mEq/L
  • DBlood pressure of 110/70 mmHg
    血壓為 110/70 mmHg
Explanation · 中文詳解

地高辛具有正性肌力與負性心率作用。成年人若心跳小於 60 下/分,易引發嚴重心搏過緩或毒性,故給藥前必須聽診心尖脈一分鐘。D、C、B 皆在安全範圍內,無需停藥。低血鉀會增加地高辛中毒風險,但此處數值正常。

Digoxin has negative chronotropic effects, so it must be withheld if the apical pulse is less than 60 beats per minute to prevent severe bradycardia. Other vital signs and potassium levels within normal ranges do not require holding the medication.

✦ 台美臨床差異

美台臨床對於 Digoxin 給藥標準皆為 60 bpm,但台灣藥師或醫師常會要求嚴格紀錄與核對心電圖。

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