— 藥理與非經腸給藥 · EASY · MCQ —
病人被開立華法林（Warfarin）治療。護理師應監測何項實驗室數據以評估藥物療效？
A client is prescribed warfarin therapy. Which laboratory value should the nurse monitor to evaluate the effectiveness of the medication?
- AInternational Normalized Ratio (INR)✓ 正解國際標準化比值 (INR)
- BPlatelet count血小板計數
- CActivated partial thromboplastin time (aPTT)活化部分凝血活酶時間 (aPTT)
- DProthrombin time (PT)凝血酶原時間 (PT)
— Explanation · 中文詳解 —
華法林（Warfarin）是一種維生素 K 拮抗劑（Vitamin K Antagonist），其作用機轉是抑制維生素 K 依賴性凝血因子的合成。由於不同實驗室對凝血酶原時間（PT）的測量標準不同，國際標準化比值（INR）被建立用來作為評估華法林治療效果的標準指標。監測 INR 能夠確保病人的抗凝血程度在安全有效的治療區間內，避免過度抗凝導致出血或抗凝不足導致血栓。
The International Normalized Ratio (INR) is the standardized measure used to monitor warfarin therapy because it accounts for variations in prothrombin time testing across different laboratories. Monitoring INR ensures the client remains within the therapeutic range to prevent clotting while minimizing the risk of bleeding complications.