— 藥理與非經腸給藥 · HARD · SATA —
病人開立 Alendronate（骨質疏鬆藥）。下列哪些指導是正確的？（選所有適合的）
Which of the following instructions are correct for a client prescribed alendronate? (Select all that apply.)
- ATake with a full glass of water✓ 正解用一杯滿的水送服
- BRemain upright for at least 30 minutes after taking✓ 正解服用後保持直立姿勢至少30分鐘
- CTake immediately before going to bed就寢前立即服用
- DTake on an empty stomach✓ 正解空腹服用
- ETake with orange juice to enhance absorption與柳橙汁同服以增強吸收
— Explanation · 中文詳解 —
Alendronate 屬於雙磷酸鹽類，對食道有極高刺激性，易引起食道潰瘍。給藥時需空腹、配一大杯水，且服藥後必須維持站姿或坐姿至少 30 分鐘，以防藥物逆流。果汁會干擾吸收（E 錯誤），睡前服用會增加逆流風險（C 錯誤）。
Alendronate is highly irritating to the esophagus and can cause ulcers, so it must be taken on an empty stomach with a full glass of water. The client should remain upright for at least 30 minutes after ingestion to prevent reflux and ensure the medication reaches the stomach. Avoid taking it with orange juice or immediately before bed, as these practices decrease absorption or increase reflux risk.
✦ 台美臨床差異
兩地對此藥的衛教重點完全一致，皆因其食道潰瘍風險而納入重要衛教範疇。