— 藥理與非經腸給藥 · EASY · SATA —
下列哪些藥物應隨餐服用以減少對胃部的刺激？（選所有適合的）
Which of the following medications should be administered with food to prevent gastric irritation? (Select all that apply.)
- AIbuprofen✓ 正解布洛芬
- BPrednisone✓ 正解潑尼松
- CMetformin✓ 正解美福明
- DLevothyroxine左甲狀腺素
- EFerrous sulfate✓ 正解硫酸亞鐵
— Explanation · 中文詳解 —
許多藥物具有潛在的胃黏膜刺激性，如非類固醇消炎藥（NSAIDs）、類固醇、雙胍類降血糖藥及鐵劑。隨餐或飯後服用可透過緩衝作用降低胃酸與黏膜接觸的傷害。甲狀腺素（Levothyroxine）則相反，需空腹以維持最佳吸收率。
Many medications can irritate the gastric mucosa, such as NSAIDs, corticosteroids, biguanide oral hypoglycemics, and iron supplements. Taking them with or after meals uses food as a buffer to reduce mucosal contact with gastric acid. In contrast, levothyroxine should be taken on an empty stomach to maintain optimal absorption.
✦ 台美臨床差異
台灣醫師常會隨藥開立胃藥（PPI/H2 blocker）以降低刺激，美國則更強調服藥時間點的調整。