— 藥理與非經腸給藥 · MEDIUM · MCQ —
對於慢性腎臟病病人，下列何種指標代表紅血球生成素（Epoetin alfa）治療有效？
Which of the following findings indicates the therapeutic effectiveness of epoetin alfa in a client with chronic kidney disease?
- AIncreased hemoglobin levels✓ 正解血紅素水平增加
- BImproved appetite食慾改善
- CDecreased blood pressure血壓下降
- DReduced serum potassium levels血清鉀濃度降低
— Explanation · 中文詳解 —
Epoetin alfa 的作用機轉是刺激骨髓造血，主要用於治療腎性貧血。當治療有效時，病人的血紅素（Hemoglobin）濃度應會上升，進而改善因貧血引起的疲倦與虛弱感。其他選項與藥物主要目標無直接關聯。
Epoetin alfa works by stimulating bone marrow erythropoiesis and is used primarily to treat anemia of renal disease. When therapy is effective, the client's hemoglobin level should rise, thereby improving fatigue and weakness caused by anemia. The other options have no direct relationship to the primary therapeutic goal of this medication.
✦ 台美臨床差異
美國常需嚴格監測 Target Hgb (10-12 g/dL) 以防過高導致心血管風險，台灣亦遵循此指引，但醫療費用給付審核較為嚴格。