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藥理與非經腸給藥 · EASY · MCQ

護理師教導病人如何使用舌下含服硝酸甘油(Nitroglycerin)緩解胸痛。哪項陳述顯示病人已理解?

A nurse is teaching a client about taking sublingual nitroglycerin for chest pain. Which statement indicates the client understands?

  • AI will swallow the tablet with a full glass of water
    我會用一杯水吞下藥片
  • BI can crush the tablet if it is too hard to dissolve
    如果藥片太難溶解,我可以將其壓碎
  • CI should take a tablet every hour if pain persists
    如果疼痛持續,我應該每小時服用一片
  • DI will place the tablet under my tongue until it dissolves✓ 正解
    我會將藥片放在舌下直到溶解
Explanation · 中文詳解

舌下含服硝酸甘油(Nitroglycerin)是緩解心絞痛的急救方式,藥物透過舌下豐富的黏膜血管直接進入血液循環,避免經過肝臟的首過效應(First-pass metabolism),從而達到快速擴張血管、降低心肌耗氧量的效果。病人必須理解藥物應放置於舌下直至溶解,不可吞服,否則藥效會因胃酸破壞或肝臟代謝而大打折扣。

Sublingual nitroglycerin is an emergency treatment for angina. The medication enters circulation directly through the rich vascular network beneath the tongue, bypassing first-pass hepatic metabolism and producing rapid vasodilation that reduces myocardial oxygen demand. The client must understand that the tablet should be placed under the tongue until dissolved and must not be swallowed; otherwise, gastric acid destruction or hepatic metabolism would greatly diminish its effect.

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