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藥理與非經腸給藥 · HARD · MCQ

護理師指導病人服用碳酸鋰(Lithium)。病人下列敘述何者顯示對藥物安全有正確認知?

A nurse is teaching a client about lithium carbonate. Which statement by the client indicates an understanding of the medication safety?

  • AI should reduce my salt intake while taking this drug
    服用此藥物期間我應減少鹽分攝取。
  • BI need to take my medication on an empty stomach
    我需要空腹服用藥物。
  • CIf I feel nauseous, I should skip my next dose
    如果我感到噁心,我應該跳過下一劑。
  • DI will drink at least 2 to 3 liters of fluid daily✓ 正解
    我每天至少會攝取 2 至 3 公升的水分。
Explanation · 中文詳解

鋰鹽治療指數狹窄,易發生中毒。鈉與鋰在腎臟競爭排除,攝取過少鹽分會導致鋰滯留。因此,病人需維持穩定且正常的鈉攝取量與充足的水分攝取(2-3 L),以確保鋰濃度穩定排除。噁心是常見症狀,不可自行停藥;隨餐服用可減少腸胃刺激,而非空腹。

Lithium has a narrow therapeutic index and is prone to toxicity. Sodium and lithium compete for excretion in the kidney; inadequate salt intake leads to lithium retention. Therefore, the patient must maintain a stable, normal sodium intake and adequate fluid intake (2-3 L) to ensure stable lithium excretion. Nausea is a common symptom, and the medication must not be self-discontinued; taking it with food can reduce gastrointestinal irritation, rather than taking it on an empty stomach.

✦ 台美臨床差異

美台精神科醫師皆強調鋰鹽病人需規則監測血中濃度與充足飲水。

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