— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師準備對心房顫動病人給予 warfarin，下列哪個檢驗數據需立即介入？
A nurse is preparing to administer warfarin to a client with atrial fibrillation. Which lab result requires immediate nursing intervention?
- APT 12 secondsPT 12 秒
- BINR 5.5✓ 正解INR 5.5
- CaPTT 35 secondsaPTT 35 秒
- DINR 2.5INR 2.5
— Explanation · 中文詳解 —
Warfarin 的治療目標 INR 通常設定在 2.0-3.0 之間（視狀況可能略有不同）。INR 5.5 遠高於治療範圍，顯示出血風險極高，若給藥將加劇抗凝血效果，恐導致嚴重出血事件。護理師應暫停給藥並通知醫師處置，必要時準備維生素 K 作為拮抗劑。
The therapeutic INR target for warfarin is generally 2.0–3.0 (and may vary somewhat depending on the indication). An INR of 5.5 is far above the therapeutic range and indicates a very high bleeding risk; further administration would intensify anticoagulation and could lead to a serious hemorrhagic event. The nurse should hold the dose, notify the provider, and prepare vitamin K as an antidote if needed.
✦ 台美臨床差異
美國護理師常依據給定的 INR 參數表執行劑量調整，台灣則大多仍需由醫師親自調整劑量。