— 藥理與非經腸給藥 · HARD · MCQ —
護理師觀察到下列哪項發現，表示病人正從地高辛（Digoxin）治療中獲得預期效果？
Which assessment finding by the nurse indicates that the client is experiencing a therapeutic effect from digoxin?
- ADecreased serum potassium血清鉀降低
- BHeart rate of 48 bpm心率 48 bpm
- CPresence of yellow-green halos出現黃綠色光暈
- DIncreased urinary output✓ 正解尿量增加
— Explanation · 中文詳解 —
Digoxin 的治療機轉為正性肌力（Positive inotropic effect），能強化心肌收縮力。對於心臟衰竭（CHF）病人，心輸出量增加後，腎臟血流灌注改善，代謝廢物與水分排出增加。因此，尿量增加（Increased urinary output）是心衰竭症狀改善、治療有效的臨床指標。
The therapeutic mechanism of digoxin is a positive inotropic effect, which enhances myocardial contractility. In patients with congestive heart failure (CHF), an increased cardiac output improves renal perfusion, leading to increased excretion of metabolic waste and water. Therefore, increased urinary output is a clinical indicator that the heart failure symptoms are improving and that treatment is effective.