護理師照護一位感染困難梭菌（C. difficile）的病人，哪項行動對於安全與阻斷傳播最為優先？
A nurse is caring for a client with Clostridioides difficile infection. Which action is the priority to ensure safety and prevent transmission?
- AMaintain the client in a negative pressure room將案主安置於負壓隔離室
- BWear a N95 respirator mask upon entering the room進入房間時佩戴 N95 呼吸器口罩
- CUse alcohol-based hand sanitizer after patient contact接觸病人後使用酒精性乾洗手液
- DPerform hand hygiene using soap and water✓ 正解使用肥皂和水進行手部衛生
困難梭菌（Clostridioides difficile）會產生芽孢（Spores），這些芽孢對酒精具有高度抵抗力，一般的酒精性乾洗手液無法殺滅。因此，照護這類病人時，必須嚴格執行接觸隔離（Contact Precautions），並明確使用肥皂與水進行機械式洗手，利用沖洗過程將芽孢帶離手部表面，這是阻斷院內感染傳播最關鍵的步驟。
Clostridioides difficile produces spores that are highly resistant to alcohol, so standard alcohol-based hand rubs cannot kill them. Therefore, when caring for these clients, the nurse must strictly implement contact precautions and explicitly use soap and water for mechanical handwashing, relying on the rinsing process to physically remove spores from the skin surface; this is the most critical step in interrupting healthcare-associated transmission.