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藥理與非經腸給藥 · HARD · SATA

護理師指導病人服用碳酸鋰(Lithium)。下列哪些病人敘述顯示其已正確理解?(選所有適合的)

A nurse is teaching a client about lithium carbonate therapy. Which statements by the client indicate a correct understanding? (Select all that apply.)

  • AI should maintain a consistent daily intake of salt✓ 正解
    我應該保持每日恆定的鹽分攝取量
  • BI will drink 2-3 liters of fluid every day✓ 正解
    我每天會喝 2-3 公升的水
  • CI should stop taking the drug if I feel nauseated
    如果我感到噁心,我應該停止服藥
  • DI need to have my blood levels checked regularly✓ 正解
    我需要定期接受血液濃度檢測
  • EI can use ibuprofen for headache pain
    我可以用布洛芬來緩解頭痛
Explanation · 中文詳解

鋰鹽治療窗狹窄,對鈉與水分平衡極度敏感。維持鈉攝取量恆定可防止鋰濃度波動;補充足夠水分有助於腎臟代謝。需定期抽血監測鋰濃度以防中毒。C選項:噁心為常見副作用,不應自行停藥,應告知醫師調整。E選項:NSAIDs(如布洛芬)會減少鋰排出,增加中毒風險,應避免使用。

Lithium has a narrow therapeutic index (0.6-1.2 mEq/L for maintenance) and is highly sensitive to sodium and water balance. Clients must maintain consistent daily sodium intake and drink 2-3 L of fluid daily because sodium depletion or dehydration increases lithium levels and toxicity risk. Regular serum lithium monitoring is mandatory. Nausea is common but the client should not self-discontinue; NSAIDs (e.g., ibuprofen) reduce renal lithium clearance and significantly increase toxicity risk—acetaminophen is preferred.

✦ 台美臨床差異

兩地均強調鋰鹽與電解質的交互作用,但台灣對 NSAIDs 與鋰鹽的藥物警示在衛教中相對重要。

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