— 藥理與非經腸給藥 · HARD · MCQ —
一位病人在開始使用 SSRIs 後出現血清素症候群症狀。護理師預期醫囑會開立哪種藥物？
A client presents with symptoms of serotonin syndrome after starting SSRIs. Which medication order should the nurse anticipate?
- AActivated charcoal活性碳
- BFlumazenil氟馬西尼
- CNaloxone納洛酮
- DBenzodiazepines✓ 正解苯二氮平類
— Explanation · 中文詳解 —
血清素症候群的主要治療為停藥與支持性療法，當出現激動、顫抖或肌肉強直時，苯二氮平類（Benzodiazepines）是減輕肌肉痙攣與焦慮的首選藥物。Naloxone 是鴉片類拮抗劑，Flumazenil 是苯二氮平拮抗劑，活性碳對此類藥物吸收效果有限。
The primary treatment of serotonin syndrome is discontinuation of the offending agent and supportive care. When agitation, tremor, or muscle rigidity occurs, benzodiazepines are the first-line drugs for relieving muscle spasm and anxiety. Naloxone is an opioid antagonist, flumazenil is a benzodiazepine antagonist, and activated charcoal has limited effect on absorption of these medications.
✦ 台美臨床差異
台美臨床皆將 Benzodiazepines 作為處理血清素症候群引發的抽搐之首選，護理師需密切觀察呼吸狀態。