— 藥理與非經腸給藥 · MEDIUM · MCQ —
病人因深部靜脈栓塞注射肝素（Heparin）。護理師應監測哪項檢驗數值以評估治療效果？
A client is prescribed intravenous heparin for deep vein thrombosis. Which lab value should the nurse monitor to evaluate the effectiveness of this therapy?
- AProthrombin Time (PT)凝血酶原時間 (PT)
- BActivated Partial Thromboplastin Time (aPTT)✓ 正解活化部分凝血活酶時間 (aPTT)
- CInternational Normalized Ratio (INR)國際正常化比值 (INR)
- DPlatelet count血小板計數
— Explanation · 中文詳解 —
肝素（Heparin）主要影響內源性凝血路徑，因此臨床監測其抗凝血效果是使用 aPTT（或 ACT）。PT/INR 是用來監測口服抗凝血劑（如 Warfarin）的指標。血小板計數則是為了監測肝素誘發之血小板低下症（HIT），並非評估凝血效果的指標。
Heparin acts primarily on the intrinsic coagulation pathway, so its anticoagulant effect is clinically monitored with the aPTT (or ACT). PT/INR is used to monitor oral anticoagulants such as warfarin. The platelet count is used to detect heparin-induced thrombocytopenia (HIT) and is not an indicator of anticoagulant efficacy.
✦ 台美臨床差異
美台臨床皆使用 aPTT 監測 Heparin，標準化程度一致。