護理師準備給予病人 warfarin。給藥前應檢視哪項檢驗數據？
A nurse is administering a dose of warfarin to a client. Which laboratory result should the nurse review before giving the medication?
- AInternational Normalized Ratio (INR)✓ 正解國際標準化比值 (INR)
- BActivated Partial Thromboplastin Time (aPTT)活化部分凝血活酶時間 (aPTT)
- CHemoglobin level血紅素濃度
- DPlatelet count血小板計數
Warfarin（Coumadin）屬於維生素 K 拮抗劑，其藥效監測必須透過國際標準化比值（INR）進行。INR 反映了凝血時間的延長程度。給藥前若未檢視 INR，可能導致病人因藥效過強而發生嚴重出血，或因藥效不足而失去抗凝血保護。aPTT 則專用於監測 Heparin 的療效，臨床上必須嚴格區分。
Warfarin (Coumadin) is a vitamin K antagonist, and its therapeutic effect must be monitored using the International Normalized Ratio (INR). The INR reflects the degree of prolongation of coagulation time. Failure to review the INR before administration may result in serious bleeding due to excessive anticoagulation, or loss of anticoagulant protection due to subtherapeutic dosing. aPTT, by contrast, is used specifically to monitor heparin therapy, and the two must be strictly differentiated in clinical practice.