— 藥理與非經腸給藥 · EASY · MCQ —
病人正服用華法林(Warfarin)。護理師應優先評估哪項檢查數值以監測該藥物的治療效果?
A client is prescribed Warfarin. Which lab value should the nurse prioritize to evaluate the therapeutic effect of this medication?
- APlatelet count血小板計數
- BaPTT活化部分凝血活酶時間
- CHemoglobin血紅素
- DPT/INR✓ 正解凝血酶原時間/國際標準比值
— Explanation · 中文詳解 —
華法林主要作用於維生素 K 依賴性凝血因子,臨床上透過測定凝血酶原時間(PT)及其標準化比值(INR)來評估其抗凝血療效,以維持目標治療範圍並預防出血或血栓風險。aPTT 用於監測肝素(Heparin),血小板與血紅素則與抗凝治療療效監測無直接關聯。
Warfarin acts primarily on the vitamin K-dependent clotting factors. Clinically, its anticoagulant effect is evaluated using the prothrombin time (PT) and the international normalized ratio (INR) to maintain the target therapeutic range and prevent bleeding or thrombotic risk. aPTT is used to monitor heparin, while platelet count and hemoglobin are not directly related to monitoring the therapeutic effect of anticoagulation.
✦ 台美臨床差異
台美臨床對於 INR 的目標範圍界定一致,但台灣常規檢查中 PT/INR 報告速度極快,護理師需確認醫囑目標值。