— 降低風險 · MEDIUM · MCQ —
一位深層靜脈血栓(DVT)病人正接受肝素(Heparin)治療。護理師應監測下列哪個實驗室數值?
A nurse is caring for a client with deep vein thrombosis (DVT) receiving heparin therapy. Which lab value should the nurse monitor?
- AActivated Partial Thromboplastin Time (aPTT)✓ 正解活化部分凝血活酶時間(aPTT)
- BInternational Normalized Ratio (INR)國際標準化比值(INR)
- CPlatelet count血小板計數
- DProthrombin Time (PT)凝血酶原時間(PT)
— Explanation · 中文詳解 —
肝素(Heparin)的抗凝血效果需透過 aPTT 監測,以確保達到治療範圍(通常為控制值的 1.5-2.5 倍)。PT/INR 是監測華法林(Warfarin)的指標。血小板計數(C)雖也重要(用於監測 HIT),但評估肝素抗凝效果的核心指標為 aPTT。
The anticoagulant effect of heparin is monitored by aPTT to ensure the therapeutic range is achieved (typically 1.5 to 2.5 times the control). PT/INR are indicators used to monitor warfarin. Although platelet count (C) is also important (for monitoring HIT), the central laboratory indicator for evaluating the anticoagulant effect of heparin is aPTT.
✦ 台美臨床差異
美台臨床皆採用 aPTT 作為肝素監測基準,但美國許多醫院已全面改用 Anti-Xa 水準監測以求更精確的劑量調整。