— 藥理與非經腸給藥 · HARD · SATA —
護理師正在照護一位因子癲前症接受硫酸鎂輸注的病人。下列哪些臨床發現應視為硫酸鎂中毒徵兆?(選所有適合的)
A nurse is caring for a client receiving intravenous magnesium sulfate for pre-eclampsia. Which findings should the nurse identify as signs of magnesium toxicity? (Select all that apply.)
- ARespiratory rate of 10 breaths/min✓ 正解呼吸頻率為 10 次/分
- BAbsent deep tendon reflexes✓ 正解深部肌腱反射消失
- CUrinary output of 40 mL/hr尿液輸出量為 40 mL/小時
- DSerum magnesium level of 10 mg/dL✓ 正解血清鎂濃度為 10 mg/dL
- EHypotension✓ 正解低血壓
— Explanation · 中文詳解 —
硫酸鎂治療子癲前症時,其治療範圍狹窄,中毒徵兆包含:呼吸抑制(<12 次/分)、深部肌腱反射消失(這通常是中毒的最早跡象)、血鎂過高(正常約 1.7-2.2 mEq/L,中毒常 >7-9 mg/dL)、低血壓及心跳過慢。尿量 40 mL/hr 是正常的,代表腎功能足夠排泄鎂離子,非中毒徵兆。
Signs of magnesium toxicity include respiratory depression (rate less than 12 breaths/min), absent deep tendon reflexes, serum magnesium levels exceeding 7-9 mg/dL, and hypotension due to vasodilation. A urinary output of 40 mL/hr is adequate and indicates proper renal function for excreting magnesium, so it is not a sign of toxicity.
✦ 台美臨床差異
兩地產科護理皆嚴格執行硫酸鎂的安全給藥流程,備有鈣劑(Calcium Gluconate)作為解毒劑。