— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師為糖尿病病人施打甘精胰島素(Glargine)。關於此種胰島素,哪項特性最需要被記住?
A nurse is administering insulin glargine to a patient with diabetes. Which characteristic of this insulin is most important to remember?
- AIt cannot be mixed with other insulins✓ 正解不可與其他胰島素混合
- BIt is a rapid-acting insulin屬於速效型胰島素
- CIt must be given before every meal必須在每餐前給藥
- DIt has a peak effect in 2 to 4 hours在 2 至 4 小時內達到峰值效應
— Explanation · 中文詳解 —
甘精胰島素屬於長效型(basal)胰島素,其作用時間長達 24 小時且無明顯高峰。最關鍵的特性是其 pH 值與其他胰島素不同,若混合會產生沉澱並導致藥效改變,因此絕對不可與其他類型胰島素在同一針筒內混和。
Insulin glargine is a long-acting, peakless basal insulin that should not be mixed with other insulins due to its acidic pH. Mixing it can cause precipitation and alter the medication's pharmacokinetic profile, potentially compromising glycemic control.
✦ 台美臨床差異
美台醫療規範皆禁止混和甘精胰島素,此觀念均為護理臨床安全之核心。