— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師準備給予病人 Vancomycin 1g IVPB。下列哪項護理措施最能預防紅人症候群？
A nurse is preparing to administer Vancomycin 1g IVPB to a client. Which nursing action is most appropriate to prevent Red Man Syndrome?
- AVerify the serum creatinine levels before administration給藥前核對血清肌酸酐濃度
- BPre-medicate the patient with acetaminophen給藥前為病人施用乙醯胺酚
- CAdminister the infusion over at least 60 minutes✓ 正解將輸注時間延長至至少 60 分鐘
- DFlush the IV line with 10mL of normal saline以 10mL 生理食鹽水沖洗靜脈管路
— Explanation · 中文詳解 —
紅人症候群是因 Vancomycin 輸注速度過快導致組織胺大量釋放。標準規範應至少給予 60 分鐘以上，若劑量大於 1g 則建議更長。此反應並非過敏，而是輸注相關效應，透過減慢速度即可有效緩解或預防。
Red Man Syndrome is caused by rapid infusion of vancomycin, which triggers histamine release leading to flushing and pruritus. To prevent this reaction, the medication should be administered slowly over at least 60 minutes, or longer for doses exceeding 1 gram.
✦ 台美臨床差異
美台臨床對於 Vancomycin 給藥速度監控皆嚴格，但美國護理師對輸注幫浦設定有更高自主權。