— 藥理與非經腸給藥 · EASY · MCQ —
護理師準備給予病人華法林 (Warfarin)。應優先查閱哪項實驗室檢測值？
A nurse is preparing to administer warfarin to a client. Which laboratory result should be reviewed first?
- AHemoglobin and hematocrit血紅素和血球容積
- BPartial thromboplastin time (PTT)部分凝血活酶時間 (PTT)
- CProthrombin time (PT) and INR✓ 正解凝血酶原時間 (PT) 和國際標準化比值 (INR)
- DPlatelet count血小板計數
— Explanation · 中文詳解 —
華法林為維生素 K 拮抗劑，透過影響凝血因子合成達到抗凝血效果。監測藥物效應的標準指標是 PT/INR。PTT 是監測肝素 (Heparin) 的指標，血小板則是監測 HIT 風險，血紅素用於評估貧血，與華法林劑量調整無直接關聯。
Warfarin is a vitamin K antagonist that exerts its anticoagulant effect by interfering with the synthesis of clotting factors. The standard parameters for monitoring its therapeutic effect are PT/INR. PTT is used to monitor heparin therapy, platelets are monitored for HIT risk, and hemoglobin is used to evaluate anemia; none of these are directly related to warfarin dose adjustment.
✦ 台美臨床差異
無顯著差異，皆依照國際標準化比值 (INR) 進行臨床決策。