— 藥理與非經腸給藥 · HARD · SATA —
下列哪些藥物需要監測肝功能檢測(LFTs)?(選所有適合的)
Which of the following medications require monitoring of liver function tests? (Select all that apply.)
- AAcetaminophen✓ 正解乙醯胺酚
- BAtorvastatin✓ 正解阿托伐他汀
- CIsoniazid✓ 正解異煙肼
- DPenicillin盤尼西林
- EMethotrexate✓ 正解甲氨蝶呤
— Explanation · 中文詳解 —
許多藥物經肝臟代謝並具潛在肝毒性,包括 Acetaminophen(高劑量)、Atorvastatin(史他汀)、Isoniazid(抗結核藥)及 Methotrexate(化療藥)。Penicillin 主要經由腎臟排泄,不需常規監測肝功能。
Acetaminophen, atorvastatin, isoniazid, and methotrexate are all associated with potential hepatotoxicity and require regular monitoring of liver function tests. In contrast, penicillin is primarily excreted by the kidneys and does not typically necessitate liver monitoring.
✦ 台美臨床差異
美國醫護系統常自動排程檢查肝指數,台灣則由專科醫師在開藥時排檢。