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藥理與非經腸給藥 · MEDIUM · MCQ

服用 Hydrochlorothiazide (HCTZ) 常見哪種電解質失衡?

Which electrolyte imbalance is common with Hydrochlorothiazide (HCTZ)?

  • AHyponatremia
    低鈉血症
  • BHyperkalemia
    高鉀血症
  • CHypercalcemia
    高鈣血症
  • DHypokalemia✓ 正解
    低鉀血症
Explanation · 中文詳解

氫氯噻嗪(Hydrochlorothiazide, HCTZ)屬於噻嗪類利尿劑(Thiazide diuretics),主要作用於腎臟遠端曲小管,抑制鈉與氯離子的再吸收。由於增加了鈉離子的排出,水分隨之排出以達到利尿效果,但此過程同時會促進鉀離子的排泄,長期使用極易導致低鉀血症(Hypokalemia)。臨床護理重點在於監測血鉀濃度,並教育病人攝取富含鉀的食物(如香蕉、柑橘、馬鈴薯)或遵醫囑補充鉀離子製劑,以維持心肌與神經肌肉的正常功能。

Hydrochlorothiazide (HCTZ) is a thiazide diuretic that acts primarily on the distal convoluted tubule of the kidney, inhibiting sodium and chloride reabsorption. Because of increased sodium excretion, water is excreted as well, producing a diuretic effect; this process also promotes potassium excretion, and long-term use easily leads to hypokalemia. Clinically, nursing focuses on monitoring serum potassium and educating the patient to consume potassium-rich foods (such as bananas, citrus, and potatoes) or take a potassium supplement as ordered to maintain normal myocardial and neuromuscular function.

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